Specific objectives
1
To identify centres of excellence in TBI patient management
2
To disseminate the results of the project to the various target groups
3
To describe the epidemiology of moderate to severe TBI in seven countries
4
To build a prognostic model based on appropriate short- and long-term outcome measures
5
To identify determinants of optimal vs. suboptimal performance
6
To validate the CREACTIVE Petal in order to better characterise TBI patients across Europe
7
to contribute to determining the most effective clinical interventions for optimally treating TBI patients
8
To join forces in the fields of data sharing and database compatibility with the international collaborative initiative on TBI
9
To consolidate a network based on the existing PROSAFE consortium in order to set up an open-source database to collect data on moderate to severe TBI patients
10
To establish a dedicated repository to house and analyse biological samples from a selected subset of TBI patients, in order to identify prognostic markers and genetic predispositions to TBI complications and outcome;
11
To establish a clinical image repository to collect anonymized clinical imaging data in order to evaluate variability in the progression of both the haemorrhagic lesion and the perilesional oedema and to assess their association with the outcome
